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 Glial and vascular contributions to neurodegenerative diseases
2022
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TDP-43 represses cryptic exons in TFIIH components to regulate epigenetic remodeling at neuronal enhancers
Sarah Hill1, Sahba Seddighi1,Yue Qi1, Wei Wu2, William Nathan2, Dongpeng Wang2, Elsa Callen2, Daniel Ramos1, Joel Reyes1, Caroline Esnault3, Ryan Dale3, Steven Coon3, Mercedes Prudencio4, Leonard Petrucelli4, Zhe Liu5, Jennifer Lippincott-Schwartz5, Andre Nussenzweig2, Michael Ward1
1NINDS/NIH, Bethesda, USA
2NCI/NIH, Bethesda, USA
3NICHD/NIH, Bethesda, USA
4Mayo Clinic, Jacksonville, USA,
5Janelia Research Campus, Ashburn, USA
Blood-brain barrier leakage in cerebral amyloid angiopathy
1 1 1 1 Sabine Voigt , K. Kaushik , M. R. Schipper1, R. G. J. van der Zwet , R. van Dort ,
J. J. de Jong2, W. H. Backes2, S. J. van Veluw1,3,4, E. I. Hoff5, J. Staals2, M. J. P. van Osch1, M. A. A. van Walderveen1, M. J. H. Wermer1, W. M. Freeze1
1Leiden University Medical Center, Leiden, The Netherlands
2Maastricht University Medical Center, Maastricht, The Netherlands
3J. Philip Kistler Stroke Research Center, Boston, USA
4MassGeneral Institute for Neurodegenerative Disease, Charlestown, USA 5Zuyderland Medical Center, Heerlen, The Netherlands
Involvement of autophagy in small vessel disease using CADASIL Notch3 disease animal models
Wenchao Shao1
1Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden
Insights into the mechanisms and factors initiating pathologic consequences in microvessels after neural injury
Tian Zhou1, Yiming Zheng1, Grace Hammel1, Li Sun1, Smaranda Ruxandra Badea2, Haitao Sun2, Choogon Li1, Timothy Megraw1, Wutian Wu2, Yi Ren1
1Florida State University College of Medicine, TALLAHASSEE, USA
2School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Single cell sequencing-based exploration of microglia subpopulations in accelerated aging mice.
Robert-Josep Subirana-Slotos1, Sebastian Kunz2, Matthias Klein2,Tobias Bopp2, Kristina Endres1
1Department of Psychiatry and Psychotherapy, University Medical Center, Mainz, Germany
2Institute for Immunology, University Medical Center, Johannes Gutenberg-Universität, Mainz, Germany
Poster Session II,Tuesday 11 October,18.00 - 19.30
10 -12 October
Divani Acropolis Athens Greece
PROGRAM & ABSTRACTS • 41






























































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