Page 38 - ISMND_PROGRAM
P. 38

 Glial and vascular contributions to neurodegenerative diseases
Poster Session II,Tuesday 11 October,18.00 - 19.30
PP49
VIRTUAL
Attenuation of progressive Alzheimer’s Disease-like Pathology by Pharmacologic inhibition and Genetic deletion of Bach1 in the APP/PS1 mouse
Debashis Dutta1,2, Christopher Ye In Kwon10, Manuj Ahuja1,2,7, Navneet Ammal Kaidery1,2, Joyce Meints10, Otis C Attucks8, Carmen Valcarce8, Sudarshana Sharma5,6,
Mitsuyo Matsumoto9, Kazuhiko Igarashi9, Michael K Lee10, Bobby Thomas1,2,3,4
1Darby Children’s Research Institute, Medical University of South Carolina, Charleston, USA
2Departments of Pediatrics, Medical University of South Carolina, Charleston, USA
3Department of Neuroscience, Medical University of South Carolina, Charleston, USA
4Department of Drug Discovery, Medical University of South Carolina, Charleston, USA
5Department of Biochemistry, Medical University of South Carolina, Charleston, USA
6Hollings Cancer Center, Medical University of South Carolina, Charleston, USA
7Department of Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, USA
8vTv Therapeutics LLC, High Point, USA
9Department of Biochemistry, Tohoku University, Graduate School of Medicine, Sendai, Japan
10Department of Neuroscience, University of Minnesota, Minneapolis, USA
A novel isolation method for spontaneously released extracellular vesicles from brain tissue and its implications for stress-driven brain pathology
Patrícia Gomes1,2, A. Catarina Vilaça-Ferreira1,2, Cristian Bodo3, Carlos Nogueras-Ortiz4, Martina Samiotaki5, Minghao Chen6,7, Carina Soares-Cunha1,2, Joana M. Silva1,2, Bárbara Coimbra1,2, George Stamatakis5, Liliana Santos1,2, George Panayotou5, Foteini Tzouanou8, Clarissa L. Waites9, Christos Gatsogiannis6,7, Nuno Sousa1,2,
Dimitrios Kapogiannis4, Bruno Costa-Silva3, Ioannis Sotiropoulos1,2,8
1Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Campus de Gualtar, Braga, 4710-057, Portugal 2ICVS/3B’s - PT Government Associate Laboratory, Braga/Guimarães, Portugal
3Systems Oncology Group, Champalimaud Research, Champalimaud Centre for the Unknown, Lisbon, 1400-038, Portugal
4Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, NIH, Baltimore, USA
5Institute for Bioinnovation, Biomedical Sciences Research Center “Alexander Fleming”, Attica, Greece
6Center for Soft Nanoscience and Institute of Medical Physics and Biophysics, University of Muenster, Muenster, 48149, Germany
7Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, Dortmund, 44227, Germany
8Institute of Biosciences & Applications NCSR "Demokritos", Athens, Greece
9Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer’s Disease and the Aging Brain, Columbia University Medical Center, New York, USA
Frontal cortex Angiotensin type 2 receptor-interacting protein levels are associated with less brain amyloid-β burden in postmortem brains of older adults with Alzheimer’s dementia
Caglar Cosarderelioglu1, Alma Plaza-Rodriguez2, Pablo Iglesias3, Simion Kreimer4,
C. Conover Talbot Jr.5, D. Brian Foster6, Robert N. Cole4, Jeremy Walston1, Peter Abadir1 1Division of Geriatric Medicine and Gerontology, Johns Hopkins University School of Medicine, Baltimore, USA
2Krieger School of Arts and Sciences, Johns Hopkins University, Baltimore, USA
3Department of Electrical and Computer Engineering, Whiting School of Engineering, Johns Hopkins University, Baltimore, USA 4The Mass Spectrometry and Proteomics Facility, The Johns Hopkins University School of Medicine , Baltimore, USA
5Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, USA
6Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, USA
PP50
PP51
VIRTUAL
38 • ISMND 2022
10 -12 October
Divani Acropolis Athens Greece
2022

























































   36   37   38   39   40