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 Glial and vascular contributions to neurodegenerative diseases
2022
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Extracellular matrix protein decorin is increased in CSF of App
knock-in mice and early stage of Alzheimer’s disease
Richeng Jiang1, Una Smailovic1, Hazal Haytural1, Betty M. Tijms2, Hao Li1,
Robert Mihai Haret3, Ganna Shevchenko4, Gefei Chen5, Axel Abelein5,
Johan Gobom6,7, Susanne Frykman1, Misaki Sekiguchi8, Ryo Fujioka8,
Naoto Watamura8, Hiroki Sasaguri8, Sofie Nyström9, Per Hammarström9, Takaomi Saido8, Vesna Jelic1, Stina Syvänen10, Henrik Zetterberg6,7,11,12,13, Bengt Winblad1,
Jonas Bergquist4, Pieter Jelle Visser1,2,14, Per Nilsson1
1Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden
2Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands 3Division of Physiology and Neuroscience, Carol Davila University of Medicine and Pharmacy , Bucharest, Romania
4Department of Chemistry – BMC, Analytical Chemistry and Neurochemistry, Uppsala University, Uppsala, Sweden
5Department of Biosciences and Nutrition, Karolinska Institutet , Huddinge, Sweden
6Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden
7Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital , Mölndal, Sweden
8Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Wako, Japan
9IFM-Department of Physics, Chemistry and Biology, Linköping University, Linköping, Sweden
10Molecular Geriatrics, Department of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden
11Department of Neurodegenerative Disease, UCL Institute of Neurology, London, United Kingdom
12UK Dementia Research Institute at UCL, London, United Kingdom
13Hong Kong Center for Neurodegenerative Diseases, Hong Kong, China
14Alzheimer Center Limburg, School for Mental Health and Neuroscience, Maastricht University, Maastricht, the Netherlands
Increased neuroinflammation is related to memory impairment in Down syndrome animal model
Larissa Estessi De Souza1, Manuella Penido da Silva1, Caroline Cristiano Real1, Carlos Alberto Buchpiguel1, Daniele de Paula Faria1
1Universidade De São Paulo, São Paulo, Brazil
Tau mediates the neuroprotective process of glial lipid droplet formation during neuronal oxidative stress
Lindsey Goodman1,2, Isha Ralhan3, Zhongyuan Zuo1,2, Oguz Kanca1,2,Ye-Jin Park1,2, Matthew Moulton1,2, Maria Ioannou3, Hugo Bellen1,2
1Baylor College Of Medicine, Texas, USA
2Jan and Dan Duncan Neurological Research Institute, Houston, Texas
3University of Alberta, Edmonton, Canada
The effect of serum on human astrocyte reactivity and their extracellular vesicles in vitro
Katherine White1, Daniel Scott1, Robert Layfield1, Sebastien Serres1 1School of Life Sciences, University Of Nottingham, Nottingham, United Kingdom
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VIRTUAL
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VIRTUAL
Poster Session I, Monday 10 October, 18.00 - 19.30
10 -12 October
Divani Acropolis Athens Greece
PROGRAM & ABSTRACTS • 35

























































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