Page 32 - ISMND_PROGRAM
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 Glial and vascular contributions to neurodegenerative diseases
Poster Session I, Monday 10 October, 18.00 - 19.30
PP20
Cell metabolism orchestrates innate immune responses of microglial cells: Where do we stand and how we move forward? Novel insights on citrate cycle reprograming during microglial inflammatory activation Canelif Yilmaz1, Eleftheria Karadima1, Georgia Fodelianaki1, Anupam Sinha1,
Anke Witt2, Sofia Traikov3, Nicola Zamboni4, Alessandra Palladini5, Ünal Coskun5, Panayotis Verginis6, Mirko Peitzsch1, Triantafyllos Chavakis1, Vasileia-Ismini Alexaki1 1Institute of Clinical Chemistry and Laboratory Medicine, University Clinic, Medical Faculty, Technische Universität Dresden, Dresden, Germany 2Department of Physiology, Medical Faculty, Technische Universität Dresden, Dresden, Germany
3Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany
4Institute for Molecular Systems Biology, ETH Zurich, Zurich, Switzerland
5Center for membrane biochemistry and lipid research, Technische Unversität Dresden, Dresden, Germany
6Laboratory of Immune Regulation and Tolerance, Division of Basic Sciences, Medical School, University of Crete, Heraklion, Greece
Brain extracellular vesicles reveal common molecular mechanisms
of neuronal insult between Alzheimer’s disease and Schizophrenia Xavier Gallart-palau1, Cristina Lorca1,2, Alina Onoiu1, Aida Serra1,2
1Biomedical Research Institute of Lleida Dr. Pifarré Foundation (IRBLLEIDA) - +Pec Proteomics Research Group (+PPRG) - Neuroscience Area – University Hospital Arnau de Vilanova (HUAV), Xavier Gallart-Palau: [email protected], Lleida, 25198, Spain; , Lleida, Spain
2IMDEA-Food Research Institute, Campus of International Excellence UAM+CSIC, Old Cantoblanco Hospital, 8 Crta. Canto Blanco,, Madrid, Spain
Translocator protein (18 kDa) regulates microglial synaptic engulfment in synucleinopathy
Yuan Shi1,2,3, Mochen Cui1,2,4, Juan Zu1,2,4, Jochen Herms1,2,3
1Center for Neuropathology, Ludwig Maximilian University of Munich, Munich, Germany
2Department of Translational Brain Research, German Center for Neurodegenerative Diseases (DZNE), Munich, Germany 3Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
4Munich Medical Research School, Ludwig Maximilian University of Munich, Munich, Germany
Protective mechanism of APOE3-Christchurch in Alzheimer’s disease
1 1 1 1 Ana-Caroline Raulin , Cynthia Linares , Lindsey Kuchenbecker , Sydney V. Doss ,
Maxwell Dacquel1,Yuka A. Martens1, Chia-Chen Liu1, Guojun Bu1
1Mayo Clinic, Department of Neuroscience, Jacksonville, USA
Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation
Fabia Filipello1, Shih Feng You1, Sidhartha Mahali1, Abhirami Kannan Iyer1,
Rita Martinez1, Olena Korvatska2, Wendy H Raskind2, Bryan Bollman3, Luca De Feo3, Laura Ghezzi3, Miguel Minaya1, Anil Cashikar1, Jun-Ichi Satoh4, Beatty Wandy5, Marina Cella6, Laura Piccio3, Celeste Karch1
1Department of Psychiatry, Washington University in St Louis, St Louis, USA
2Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, USA
3Department of Neurology, Washington University in St Louis, St Louis, USA
4Department of Bioinformatics and Molecular Neuropathology, Meiji Pharmaceutical University, Tokyo, Japan 5Department of Molecular Microbiology, Washington University School of Medicine, St Louis, USA 6Department Of Pathology and Immunology, Washington University in St Louis, St Louis, USA
PP21
PP22
PP23 PP24
VIRTUAL
32 • ISMND 2022
10 -12 October
Divani Acropolis Athens Greece
2022






























































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