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 Glial and vascular contributions to neurodegenerative diseases
2022
SCIENTIFIC PROGRAM Day 3,Wednesday October 12,2022
08:30 - 10:10
Session VII: PATHOGENIC MECHANISMS OF NEURODEGENERATION (II) Chair: Gopal Thinakaran, USF Morsani College of Medicine, USA
10:10 - 10:40 10:40 - 12:20
VIRTUAL
12:20 - 12:30
12:30 - 12:50
12:50 - 13:15
COFFEE BREAK/EXHIBITS
Session VIII: FROM MECHANISMS TO THERAPIES Chair: Sangram Sisodia, University of Chicago, USA
18 • ISMND 2022
08:30 - 08:50 08:50 - 09:10
09:10 - 09:30 09:30 - 09:50 09:50 - 10:10
Integrated Proteomics for Therapeutic Target and Biomarker Discovery in Alzheimer’s Disease
Nicholas Seyfried, Emory University School of Medicine, USA
Role of the gut microbiome in modulation of Abeta amyloidosis and neuroinflammation
Sangram Sisodia, University of Chicago, USA
Role of gamma-secretase in innate immunity and AD
Yueming Li, Memorial Sloan Kettering Cancer Center, USA Mitochondrial dysfunction in AD
Xiongwei Zhu, Case Western Reserve University, USA
Chronic Stress & exosomes: key players in progression and diagnosis of AD
Ioannis Sotiropoulos, Institute of Biosciences & Applications, NCSR “Demokritos”, Greece
10:40 - 11:00 11:00 - 11:20
11:20 - 11:40 11:40 - 12:00 12:00 - 12:20
Mechanisms and therapeutic insights for neurodegenerative disease
Leonard Petrucelli, Mayo Clinic Florida, USA
M1 muscarinic stimulation of post-synaptic receptors for the potential treatment and prevention of cognitive decline
Abraham Fisher,AD/PDTM
TDP-43: pathobiology, prognostic biomarker, and therapeutic strategy.
Philip Wong, Johns Hopkins University, USA
Therapeutic strategies targeting alpha-synuclein in AD-related dementia
Pamela McLean, Mayo Clinic Florida, USA Farnesyltransferase inhibition for Alzheimer’s disease
Robert Vassar, Northwestern University Medical School, USA 2022 BrightFocus Alzheimer’s Disease Research Awards
Travel and Diversity Award Ceremony
Talk / Poster Awards and Closing Remarks
10 -12 October
Divani Acropolis Athens Greece




























































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