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 Glial and vascular contributions to neurodegenerative diseases
2022
15:40 – 16:40
Day 2,Tuesday,October 11,2022
SHORT TALK III
Chair: Hui (Iris) Zhang, Thomas Jefferson University, USA
VIRTUAL
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The Parkinson’s disease-associated mutation LRRK2-G2019S alters astrocyte differentiation dynamics and induces senescence in midbrain organoids, Silvia Bolognin,
University Of Luxembourg, Luxembourg
TREM2 mediates microglial neuroprotection against TDP-43 neurodegeneration,
Long-Jun Wu, Mayo Clinic Minnesota, USA
Cerebrospinal fluid immunity in aging and neurodegenerative disease, David Gate,
Northwestern University, USA
Senescent-like human primary neurons undergo selective human immune NK cell-mediated clearance, Julie Andersen, Buck Institute For Research On Aging, USA
Activation of D2Rs ameliorates the dysfunction of microglia in human LRRK2-R1441G transgenic mice, Hui Zhang,Thomas Jefferson University,USA
Panel Discussion: GLIAL AND VASCULAR CONTRIBUTIONS TO NEURODEGENERATION Discussion Leaders: Guojun Bu, David Holtzman, Mathew Blurton-Jones, Justin Lee
POSTER SESSION 2
16:40 – 17:40
17:40 – 19:00
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Internalized alpha-synuclein fibrils are rapidly degraded by glial cells but stably accumulate as C-terminal truncated form in neurons: Relevance to pathogenesis of
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alpha-synucleinopathy, Michael Lee, University Of Minnesota, USA
Divani Acropolis Athens Greece
SCIENTIFIC PROGRAM
10 -12 October
PROGRAM & ABSTRACTS • 17




































































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