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 Glial and vascular contributions to neurodegenerative diseases
2022
SCIENTIFIC PROGRAM Day 2,Tuesday,October 11,2022
08:30 - 09:50
Session IV: EYEING ON THE GLIA AND VASCULATURE IN NEURODEGENERATION Chair: Hui Zheng, Baylor College of Medicine, USA
09:50 - 10:20 10:20 - 12:00
Cheryl Wellington, University of British Columbia, Canada Session V: GENETIC/GENOMIC MECHANISMS OF NEURODEGENERATION
Chair: Henrietta Nielsen, Stockholm University, Sweden
12:00 - 13:30 13:30 - 15:10
VIRTUAL VIRTUAL
VIRTUAL
15:10 - 15:40
Mark Cookson, National Institutes of Health, USA
Session VI: PATHOGENIC MECHANISMS OF NEURODEGENERATION (I)
Chair: Yueming Li, Memorial Sloan Kettering Cancer Center, USA
16 • ISMND 2022
08:30 - 08:50
08:50 - 09:10
09:10 - 09:30
09:30 - 09:50
Inter-pericyte tunnelling nanotubes: at the heart of neurovascular dysfunction in neurodegenerative diseases
Adriana Di Polo, University of Montreal, Canada
Opposite effects of APOE4 in AD and glaucoma
Oleg Butovsky, Harvard Medical School, Brigham and Women's Hospital, USA Meningeal lymphatic vasculature and apoE: a key pas de deux in AD?
Sandro Da Mesquita, Mayo Clinic Florida, USA Apolipoproteins in vasculature and Alzheimer’s disease
COFFEE BREAK/EXHIBITS
10:20 - 10:40
10:40 - 11:00
11:00 - 11:20
11:20 - 11:40
11:40 - 12:00
Genetic and functional validation of AD risk genes implicates efferocytosis
Alison Goate, Icahn School of Medicine at Mount Sinai, USA Molecular subtypes of Alzheimer’s disease
Bin Zhang, Icahn School of Medicine at Mount Sinai, USA Unravelling Alzheimer’s genetics to identify pharmacological targets
Steve Estus, University of Kentucky, USA
Genetic analysis of striatum-selective pathogenesis in Huntington’s disease
William Yang, University of California Los Angeles, USA
Genetic analyses identify microglial contributions to Parkinson’s disease
LUNCH BREAK/EXHIBITS
13:30 - 13:50 13:50 - 14:10 14:10 - 14:30
14:30 - 14:50 14:50 - 15:10
Pathogenic role of ANXA11 variants in ALS- FTD spectrum
Seung Hyum Kim, Hanyang University, South Korea Molecular approaches to tackle Parkinson’s disease
Ted Dawson, Johns Hopkins University, USA
Cell-autonomous and non-cell-automonous roles of BIN1 in neuroinflammation and tau pathology
Gopal Thinakaran, USF Morsani College of Medicine, USA
Harnessing iPSC-microglia to deliver therapeutic proteins to the brain
Mathew Blurton - Jones, University of California Irvine, USA
Single-cell dissection of the human brain vasculature in health and Huntington’s disease
Myriam Heiman, Massachusetts Institute of Technology, USA
COFFEE BREAK / EXHIBITS
10 -12 October
Divani Acropolis Athens Greece














































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