Page 15 - ISMND_PROGRAM
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 Glial and vascular contributions to neurodegenerative diseases
2022
15:20 – 15:50 15:50 – 16:50
Day 1, Monday, October 10
COFFEE BREAK / EXHIBITS
VIRTUAL
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SHORT TALK I: BrightFocus Foundation Early Career Investigator Session Chair: Sharyn Rossi, BrightFocus Foundation, USA
TREM2-independent microgliosis promotes tau-mediated neurodegeneration in the presence of ApoE4, Maud Gratuze, Washington University School of Medicine, USA
Hyperactive somatostatin interneurons near amyloid plaque and cell-type-specific firing deficits in a mouse model of Alzheimer’s disease, Moustafa Algamal, Massachusetts General Hospital & Harvard Medical School, USA
Sex chromosomes and gonads exert differential effects on neuroinflammation in an Alzheimer’s disease mouse model, Erin Reed-Geaghan, Northeast Ohio Medical University, USA
Unbiased classification of the human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment, Lenora Higginbotham, Emory University School of Medicine, USA
Anxiety associates with cerebral hyperperfusion in preclinical Alzheimer disease,
Arjun Masurkar, NYU School Of Medicine, USA
The 677C>T variant in methylenetetrahydrofolate reductase causes morphological and
functional cerebrovascular deficits in mice, Alaina Reagan,The Jackson Laboratory,USA
Understanding the impact of midlife cardiovascular risk factors & subclinical atherosclerosis on brain´s health: a role on Alzheimer's pathology, Marta Cortes-Canteli, Centro Nacional De Investigaciones Cardiovasculares & Instituto De Investigacion Sanitaria Fundacion Jimenez Diaz, Spain
BREAK
SHORT TALK II
Chair: Hongmei Li, Mayo Clinic Florida, USA
Large-scale multi-omic analyses in CSF identified several causal and druggable targets for Alzheimer’s disease, Carlos Cruchaga, Washington University in St. Louis, USA
Lysosomal signaling in microglia and Alzheimer’s disease, Harini Iyer, Stanford University, USA
Regulation of inflammasome activation in human microglia by Inositol Polyphosphate-5- Phosphatase D (INPP5D/SHIP1), Tracy L.Young-Pearse, Brigham and Women's Hospital and Harvard Medical School, USA
Canonical amyloid-β (Aβ) and tau pathologies regulate disease stage-specific microglia subtypes in AD, Tong Li, Johns Hopkins University School of Medicine, USA
Human iPSC-derived 3D tissue models to investigate glial and vascular contributions
to neurodegenerative and neurovascular diseases, Dominik Paquet, Institute for Stroke and Dementia Research (ISD), University Hospital & Munich Cluster for Systems Neurology (SyNergy), Germany
Characterization of amyloid-beta protofibrils in Alzheimer’s disease brain and unique binding properties of lecanemab, Lars Lannfelt, BioArctic, Sweden
POSTER SESSION 1 and WELCOME RECEPTION
16:50 – 17:00 17:00 – 18:00
VIRTUAL VIRTUAL
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18:00 – 19:30
Divani Acropolis Athens Greece
SCIENTIFIC PROGRAM
10 -12 October
PROGRAM & ABSTRACTS • 15






















































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